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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
10
Human Site:
S420
Identified Species:
16.92
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S420
K
S
G
N
K
R
S
S
S
H
S
S
P
G
S
Chimpanzee
Pan troglodytes
XP_509445
540
59236
G259
S
S
S
H
S
S
S
G
S
P
K
K
Q
K
S
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S420
K
S
S
S
K
R
S
S
S
H
S
S
P
G
S
Dog
Lupus familis
XP_534658
709
78944
S420
R
S
G
S
K
R
S
S
S
Q
S
S
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S423
S
S
G
K
R
S
S
S
Q
S
S
P
N
S
P
Rat
Rattus norvegicus
NP_001099399
476
51796
K195
N
I
Q
S
P
S
V
K
S
S
S
K
R
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
A417
K
S
S
C
K
R
S
A
S
Q
S
S
P
N
S
Chicken
Gallus gallus
Q5F3D1
613
68449
E332
K
R
P
K
D
D
L
E
V
A
V
A
D
M
D
Frog
Xenopus laevis
Q6DD45
743
82926
K405
G
S
S
N
K
S
N
K
R
S
S
C
Q
S
S
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
Q404
H
E
S
D
S
T
P
Q
K
T
K
K
R
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
A272
P
P
A
W
L
E
E
A
K
V
Q
S
S
G
I
Honey Bee
Apis mellifera
XP_001122586
556
62911
N275
G
I
P
V
E
D
P
N
D
E
P
G
S
I
I
Nematode Worm
Caenorhab. elegans
P34656
453
51815
A172
V
I
S
D
R
L
R
A
A
L
G
L
R
G
N
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
L345
S
N
Q
S
K
E
V
L
K
L
H
L
T
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
26.6
86.6
73.3
N.A.
33.3
20
N.A.
66.6
6.6
33.3
6.6
N.A.
13.3
0
6.6
6.6
P-Site Similarity:
100
33.3
93.3
86.6
N.A.
40
26.6
N.A.
73.3
13.3
40
13.3
N.A.
20
13.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
22
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
15
8
15
0
0
8
0
0
0
8
0
8
% D
% Glu:
0
8
0
0
8
15
8
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
22
0
0
0
0
8
0
0
8
8
0
29
0
% G
% His:
8
0
0
8
0
0
0
0
0
15
8
0
0
0
0
% H
% Ile:
0
22
0
0
0
0
0
0
0
0
0
0
0
8
15
% I
% Lys:
29
0
0
15
43
0
0
15
22
0
15
22
0
15
0
% K
% Leu:
0
0
0
0
8
8
8
8
0
15
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
8
8
0
15
0
0
8
8
0
0
0
0
8
8
8
% N
% Pro:
8
8
15
0
8
0
15
0
0
8
8
8
29
8
8
% P
% Gln:
0
0
15
0
0
0
0
8
8
15
8
0
15
0
0
% Q
% Arg:
8
8
0
0
15
29
8
0
8
0
0
0
22
0
0
% R
% Ser:
22
50
43
29
15
29
43
29
43
22
50
36
15
29
58
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% T
% Val:
8
0
0
8
0
0
15
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _